Inflammaging and the Cost of “Normal Tired”
Most people do not burn out in a blaze. They slowly unravel. Chronic fatigue, foggy thinking, stubborn weight gain, and unexplained aches are brushed off as “busy season symptoms” or the price of ambition. Yet beneath these everyday complaints lies a physiological truth: chronic low-grade inflammation.
Researchers like Dr Claudio Franceschi, who coined the term “inflammaging,” show that chronic inflammation accelerates biological aging by damaging tissues, shortening telomeres, and destabilising metabolic pathways. It is a silent fire that fuels obesity, cardiovascular disease, type 2 diabetes, and depression.
Genes load the gun, environment pulls the trigger
Behavioural and epigenetic science reveals that 70–80 percent of chronic disease risk is shaped by lifestyle, not inherited DNA (Harvard School of Public Health). Meaning: your biological age is negotiable. It can be younger or older than your years depending on how you live, rest, move, and recover.
Food as intelligence, not fuel
Every meal is a biochemical message. Ultra-processed food, seed oils, and sugary drinks activate inflammatory cytokines that keep the body in a defensive state. In contrast, traditional regional foods—lentils, barley, dates, herbs, seafood, whole grains—are naturally anti-inflammatory.
This echoes the Slow Food principles that AMT champions: local, seasonal, culturally rooted nutrition as a foundation for planetary and personal health.
The world’s Blue Zones show that longevity is less about supplements and more about culture—simplicity, daily movement, plant-forward eating, and community bonds.
Stress, screens, and the nervous system
Chronic stress distorts the vagus nerve’s signalling and traps the body in fight-or-flight mode. Studies from Stanford and UCLA link digital overload to increased inflammatory markers and poor sleep architecture. Even a ten-minute slow walk can lower sympathetic activity.
Healthspan as the new definition of success
Across forward-thinking societies the conversation is shifting from lifespan to healthspan. The question is no longer “How long can I live?” but “How well can I live for as long as possible?”
Beating inflammaging is less about perfection and more about the daily systems that support vitality—homes, workplaces, and cities designed with human wellbeing at the centre.

